Eur > medicine & health > erasmus mc > view article scopus: cited 0 times a retrospective analysis of antitumour activity with trabectedin in translocation-related sarcomas cesne, a. canada viagra for sale Le blay, j-y. Men viagra for women Verweij, j. Poveda, a. generic viagra for sale in usa Casali, p. G. Demetri, g. buy generic viagra online D. Cresta, s. Maki, r. G. Balaã±a, c. viagra mental side effects Schã¶ffski, p. Grosso, f. Lardelli, p. meaning two bathtubs viagra ads Nieto, a. Alfaro, v. buy cheap viagra thailand , et al. viagra cheap price 2012-06-29 article european journal of cancer erasmus mc: university medical center rotterdam repository contains one file which is not publicly available aims: approximately 20% of soft tissue sarcomas (sts) have subtype-specific chromosomal translocations; these generate chimeric oncoproteins which can act as abnormal transcription factors. cheapest online viagra Since trabectedin can bind to dna and displace transcription factors, antitumour activity was explored in translocation-related sarcoma (trs) subtypes. Methods: the current retrospective pooled analysis includes data from 81 patients with trs treated in 8 phase ii trials. Results: trs subtypes were: synovial sarcoma (ss, n = 45), myxoid-round cell liposarcoma (mrc-l-sarcoma, n = 27), alveolar soft part sarcoma (asps, n = 4), endometrial stromal sarcoma (ess, n = 3) and clear cell sarcoma (ccs, n = 2). do you need prescription viagra thailand All but one patient had received prior chemotherapy (median of 2 lines). do you need prescription viagra thailand Patients received a median of 4 trabectedin cycles (range, 1-48; median dose intensity = 0. 40 mg/m2/week). is there a generic viagra Partial responses according to response evaluation criteria in solid tumours (recist) occurred in 8 patients (orr = 10%; 95% ci, 4-19%): four in mrc-l-sarcoma; three in ss and one in ess. Buy viagra las vegas nv Tumour control rate (orr plus stable disease) was 59% (95% ci, 48-70%). Women taking viagra happens Median pfs was 4. viagra for women - pink 1 months (6-month pfs rate = 40%). Median overall survival was 17. 4 months (survival rate at 12 months = 60%). costs viagra viagra Trabectedin had a manageable safety profile. half viagra pill enough Conclusion: trabectedin demonstrates encouraging disease control in trs. cheapest viagra price Since these promising results were generally noted in patients following chemotherapy, a phase iii randomised trial in first-line is ongoing to compare trabectedin with doxorubicin-based chemotherapy in patients with trs. Keywords sarcoma antitumour activity chimeric fusion oncoproteins chromosomal translocation trabectedin bookmark with: cit. cheap viagra generic best price do you need prescription viagra thailand